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顆粒劑干法制粒機(jī)

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  • 公司名稱(chēng)石家莊科源機(jī)械設(shè)備有限公司
  • 品       牌
  • 型       號(hào)
  • 所  在  地石家莊市
  • 廠商性質(zhì)生產(chǎn)廠家
  • 更新時(shí)間2024/9/13 14:03:06
  • 訪問(wèn)次數(shù)7256
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  石家莊科源機(jī)械設(shè)備有限公司原石家莊市科源機(jī)械設(shè)備研究所成立于2001.4.16日,是經(jīng)河北省科委批準(zhǔn)組建的集科研、開(kāi)發(fā)、設(shè)計(jì)、制造、銷(xiāo)售于一體的機(jī)械產(chǎn)品專(zhuān)業(yè)生產(chǎn)型企業(yè),依法注冊(cè)經(jīng)營(yíng),享有獨(dú)立的經(jīng)營(yíng)權(quán)與知識(shí)產(chǎn)權(quán)。自籌建以來(lái),與河北科技大學(xué)合作,已完成了五個(gè)課題共計(jì) 26個(gè)研發(fā)項(xiàng)目,擁有一支專(zhuān)業(yè)從事干法制粒20余年的團(tuán)隊(duì),屬高科技型企業(yè)。
  干法制粒機(jī)是我公司的主導(dǎo)產(chǎn)品,該產(chǎn)品是根據(jù)醫(yī)藥行業(yè)的特點(diǎn),在消化吸收國(guó)外同類(lèi)產(chǎn)品、考慮我國(guó)國(guó)情的基礎(chǔ)上研發(fā)而成的,與國(guó)外同類(lèi)產(chǎn)品比具有很高的性能價(jià)格比。
  Founded on 16 April 2001, Shijiazhuang Keyuan Machinery & Equipment Co., Ltd., formerly known as Shijiazhuang Keyuan Machinery & Equipment Research Institute, is a professional manufacturer of machinery products approved by Hebei Science and Technology Commission, integrating scientific research, development, design, manufacturing and sale. Registered and operated according to the law, it enjoys independent management rights and intellectual property rights. Since its establishment, our company has cooperated with Hebei University of Science and Technology and completed a total of 26 research and development projects in five programs, and has been granted a number of patents. With a team specialized in dry granulation for more than 20 years, our company is a high-tech enterprise.
  The dry granulator is the only leading product of our company. According to the characteristics of the pharmaceutical industry, it is developed after digesting and absorbing similar foreign products and considering China's national conditions. It is in a leading position in China and has a very high performance-price ratio compared with similar foreign products.
  發(fā)展歷程DEVELOPMENT PATH
  2001年4月
  石家莊科源機(jī)械設(shè)備研究所注冊(cè)成立。
  Shijiazhuang Keyuan Machinery and Equipment Research Institute was incorporated
  2002年3月
  第一臺(tái)懸臂結(jié)構(gòu)臥式干法制粒機(jī)研制成功。
  The first cantilever structure horizontal dry granulator was successfully developed
  2003年1月
  石藥集團(tuán)河北中潤(rùn)制藥有限公司和我司簽訂訂購(gòu)合同,我司第一套生產(chǎn)型懸臂結(jié)構(gòu)臥式干法制粒機(jī)走入市場(chǎng)。
  Shijiazhuang Group Hebei Zhongrun Pharmaceutical Co., Ltd. signed a contract with our company, and our first production-type cantilever structure horizontal dry granulator entered the market.
  2003年09月
  為華北制藥集團(tuán)倍達(dá)有限公司維修進(jìn)口干法制粒機(jī),開(kāi)始吸收和消化國(guó)外同類(lèi)設(shè)備的成果
  結(jié)合國(guó)內(nèi)物料的情況完善設(shè)備的功能。
  Maintenance of imported dry granulator for Huabei Pharmaceutical Group Bida Co., Ltd., began to absorb and digest the results of similar equipment abroad improve the function of the equipment in combination with the situation of domestic materials.
  2004年03月
  得到石藥集團(tuán)河北中潤(rùn)制藥有限公司的認(rèn)可又和我司簽訂兩套設(shè)備訂購(gòu)合同,我司第二三套生產(chǎn)型懸臂結(jié)構(gòu)臥式干法制粒機(jī)走入市場(chǎng)。
  It was recognized by Hebei Zhongrun Pharmaceutical Co., Ltd. of Shijiazhuang Group and signed two sets of equipment ordering contracts with our company. The second and third sets of production-type cantilever structure horizontal dry granulators entered the market.
  2004-2006年
  隨著制藥、食品、化工行業(yè)內(nèi)不斷的推廣,得到更多企業(yè)的關(guān)注和訂購(gòu)。
  With the continuous promotion in the pharmaceutical, food and chemical industries, more companies pay attention and order.
  2006年07月
  第一臺(tái)實(shí)驗(yàn)型干法制粒機(jī)出口西班牙。
  The first experimental dry granulator was exported to Spain.
  2007年10月
  印度阿樂(lè)濱度公司和我司簽訂訂購(gòu)合同,第一套生產(chǎn)型懸臂臥式干法制粒機(jī)出口。從07年至今我司持續(xù)為印度阿樂(lè)濱度公司供貨多達(dá)幾十套生產(chǎn)型干法制粒機(jī)。
  India Albindu Company signed an order contract with our company and exported the first production-type cantilever horizontal dry granulator. Since 2007, our company has continued to supply up to dozens of production-type dry granulators for Albindu Company in India.
  2008年05月
  國(guó)藥集團(tuán)江陰天江藥業(yè)有限公司(國(guó)家中醫(yī)藥管理局批準(zhǔn)的"中藥飲片改革試點(diǎn)單位",通過(guò)國(guó)家GMP認(rèn)證的中藥配方顆粒生產(chǎn)企業(yè))和我司簽訂訂購(gòu)合同,我司第一套生產(chǎn)型懸臂臥式干法制粒機(jī)用于中藥配方顆粒的生產(chǎn)。從08年至今我司持續(xù)為天江藥業(yè)供貨多達(dá)十余套生產(chǎn)型干法制粒機(jī)。
  Sinopharm Jiangyin Tianjiang Pharmaceutical Co., Ltd. (a "pilot unit for reforming traditional Chinese medicine decoction pieces" approved by the State Administration of Traditional Chinese Medicine, the first Chinese medicine formula granule manufacturer that has passed the national GMP certification) signed an order contract with our company, our first set The production type cantilever horizontal dry granulator is used for the production of traditional Chinese medicine formula granules. Since 2008, our company has continued to supply more than ten production-type dry granulators for Tianjiang Pharmaceutical.
  2009-2010年
  我司生產(chǎn)型懸臂臥式干法制粒機(jī)陸續(xù)進(jìn)入東阿阿膠、康仁堂、國(guó)藥集團(tuán)德眾藥業(yè)、啟元國(guó)藥等中藥企業(yè)。
  The cantilever horizontal dry granulator produced by our company has successively entered the leading traditional Chinese medicine companies such as Donge Ejiao, Kangrentang, Sinopharm Group Dezhong Pharmaceutical, and Qiyuan Sinopharm.
  2011年04月
  科源公司順利通過(guò)“ISO9001質(zhì)量管理體系”認(rèn)證。
  Keyuan Company successfully passed the "ISO9001 Quality Management System" certification.
  2012年04月
  石家莊科源機(jī)械設(shè)備研究所更名為石家莊科源機(jī)械設(shè)備有限公司,廠址遷至石家莊市鹿泉區(qū)銅冶鎮(zhèn)綠島經(jīng)濟(jì)開(kāi)發(fā)區(qū)碧水街。
  Shijiazhuang Keyuan Machinery Equipment Research Institute was renamed Shijiazhuang Keyuan Machinery Equipment Co., Ltd., and its factory moved to Bishui Street, Ludao Economic Development Zone, Tongye Town, Luquan District, Shijiazhuang City.
  2012年-至今
  經(jīng)過(guò)多年的經(jīng)驗(yàn)積累,對(duì)同類(lèi)進(jìn)口產(chǎn)品的吸收以及反復(fù)的物料實(shí)驗(yàn),幾年間對(duì)設(shè)備進(jìn)行過(guò)三次產(chǎn)品的升級(jí),如今已服務(wù)包括國(guó)藥集團(tuán)天江藥業(yè)、國(guó)藥集團(tuán)福建承天金嶺藥業(yè)、國(guó)藥廣東一方藥業(yè)、石藥集團(tuán)、華北制藥集團(tuán)、中化帝斯曼、山東新華藥業(yè)、聯(lián)邦制藥、山東魯抗、山西威奇達(dá)、齊魯制藥、科倫藥業(yè)、麗珠集團(tuán)、天士力、伊利集團(tuán)、海南海藥、吳太感康、四川新綠色藥業(yè)、亞寶藥業(yè)、馬應(yīng)龍藥業(yè)、貴陽(yáng)新天藥業(yè)、浙江醫(yī)藥集團(tuán)、濟(jì)川藥業(yè)等多家行業(yè)企業(yè)在內(nèi)的上百家藥企。
  After years of experience accumulation, the absorption of similar imported products and repeated material experiments, the equipment has been upgraded three times in the past few years. Nowadays, the services include Sinopharm Tianjiang Pharmaceutical, Sinopharm Fujian Chengtian Jinling Pharmaceutical, Sinopharm Guangdong Yifang Pharmaceutical, CSPC, North China Pharmaceutical Group, Sinochem DSM, Shandong Xinhua Pharmaceutical, United Laboratories, Shandong Lukang, Shanxi Weiqida, Qilu Pharmaceutical, Kelun Pharmaceutical, Livzon Group, Tasly , Yili Group, Hainan Haiyao, Wu Taigankang, Sichuan New Green Pharmaceutical, Yabao Pharmaceutical, Ma Yinglong Pharmaceutical, Guiyang Xintian Pharmaceutical, Zhejiang Pharmaceutical Group, Jichuan Pharmaceutical, and many other leading enterprises in the industry Of hundreds of pharmaceutical companies.


干法制粒機(jī)
顆粒劑干法制粒機(jī)可以將藥物和輔料的粉末混合均勻、壓縮成大片狀或板狀后,粉碎成所需大小的顆粒。制粒后成品的粒度均勻,堆積密度增加、流動(dòng)性改善及可控制崩解度,同時(shí)便于后序加工、貯存和運(yùn)輸。
顆粒劑干法制粒機(jī) 產(chǎn)品信息

顆粒劑干法制粒機(jī)可以將藥物和輔料的粉末混合均勻、壓縮成大片狀或板狀后,粉碎成所需大小的顆粒。干法制粒機(jī)的主要工藝流程如下:

 1、新的濕法混合制粒機(jī)濕法混合制粒,實(shí)驗(yàn)室制粒機(jī)利用混合攪拌槳將粉料和粘合劑攪拌混合成潤(rùn)濕軟材,再由高速破碎刀切割制成濕的顆粒,目前此種方法被普遍應(yīng)用。其設(shè)備與工藝不完善之處:需要大量的粘合劑、清洗產(chǎn)生的污水對(duì)環(huán)境造成污染。另外,制出的濕顆粒目數(shù)分布范圍廣而不均勻、細(xì)粉多,一般多用于壓片貨膠囊填充。
 
2、傳統(tǒng)的濕法制粒即槽型混合機(jī)先混合成濕的“軟材”,然后通過(guò)干法制粒機(jī)進(jìn)行制粒。目前,此種方法還在被一些廠家所沿用,但此類(lèi)設(shè)備存在混合不均勻、清洗不干凈、密封不良及漏油等問(wèn)題。
 
3、一步沸騰制粒是將噴霧技術(shù)和流化技術(shù)綜合運(yùn)用,干法制粒機(jī)使傳統(tǒng)的混合、制粒、干燥過(guò)程在同一密閉容器中一次完成。同樣,其設(shè)備與工藝需用大量的粘合劑,清洗后需污水處理,且制粒時(shí)間偏長(zhǎng)。
 

干法制粒同以上3種濕法制粒相比較,具有以下的優(yōu)勢(shì):
(1)干法制粒比起濕法制粒投入設(shè)備少、維護(hù)成本低、占地面積少,故其生產(chǎn)成本低。
 (2)干法制粒比濕法制粒工藝簡(jiǎn)單,中間環(huán)節(jié)少,既可控制粉塵飛揚(yáng)又減少粉料浪費(fèi)。同時(shí),無(wú)廢氣排放、減少環(huán)境污染。
(3)干法制粒比起濕法制粒來(lái),大的優(yōu)勢(shì)是低能耗,這由于干法制粒無(wú)需加濕再干燥。
 (4)干法制粒無(wú)需添加任何粘合劑;有些藥物(抗生素類(lèi)、熱敏性強(qiáng))以及中藥提取物比重達(dá)不到要求,又不能加粘合劑,必須通過(guò)干法制粒工藝來(lái)完成。
(5)干法制粒后成品的粒度均勻,堆積密度增加、流動(dòng)性改善及可控制崩解度,同時(shí)便于后序加工、貯存和運(yùn)輸。 

技術(shù)參數(shù)

 

型號(hào)

 

 

GZL240-100l

 

 

生產(chǎn)能力

 

 

80-150kg/h

 

 

粒    徑

 

 

8~80目

 

 

壓輥尺寸(mm)

 

 

Φ240×100

 

 

zui大輥間壓力

 

 

30t

 

 

總功率

 

 

14.2kw

 

 

重    量

 

 

3噸

 

 

外形尺寸

 

 

1443mmX2014mmX2600mm

 

 

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