ATPγS四鋰鹽 (Synonyms: Adenosine-5'-O-3-thiotriphosphate (tetralithium salt); Adenosine 5'-[γ-thio]triphosphate tetralithium salt)
ATPγS (tetralithium salt) 是真核生物翻譯起始因子 eIF4A 的核苷酸水解和RNA解鏈活性的底物。
生物活性
ATPγS (tetralithium salt) is a substrate for the nucleotide hydrolysis and RNA unwinding activities of eukaryotic translation initiation factor eIF4A[1].
體外研究(In Vitro)
ATPγS (tetralithium salt) enhances intrinsic fluorescence and induces aggregation which increases the activity of spinach Rubisco activase[1].
ATPγS (50-100 μM final blood concentration) attenuates inflammatory response with decreased accumulation of cells (48%, P < 0.01) and proteins (57%, P < 0.01) in bronchoalveolar lavage and reduces neutrophil infiltration and extravasation of Evans blue albumin dye into lung tissue[3].
體內(nèi)研究(In Vivo)
ATPγS (tetralithium salt, 50 μM final, intravenous) demonstrates preserved lung parenchymal architecture[3].
ATPγS results in a dose-dependent effect on EBA extravasation in LPS-treated mice[3].
分子量:546.98
Formula:C10H12Li4N5O12P3S
CAS 號:93839-89-5
運輸條件:Room temperature in continental US; may vary elsewhere.
儲存方式
-20°C, sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
參考文獻
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注:產(chǎn)品僅用于科研