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高遷移率族蛋白1(HMGB1)多克隆抗體

參考價￥1436.00
具體成交價以合同協(xié)議為準(zhǔn)
  • 公司名稱杭州昊鑫生物科技股份有限公司
  • 品       牌云克隆
  • 型       號PAA399Ra01
  • 所  在  地杭州市
  • 廠商性質(zhì)代理商
  • 更新時間2024/7/11 15:07:43
  • 訪問次數(shù)192
規(guī)格
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杭州昊鑫生物科技股份有限公司成立于2009年初，是一家面向生命科學(xué)領(lǐng)域，從事科研機構(gòu)、高校、院所及生產(chǎn)企業(yè)所需科研試劑、耗材，儀器銷售和服務(wù)面向全國。

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胎牛血清、MCE抑制劑激動劑、RNA提取試劑盒、ELISA試劑盒、重組蛋白
產(chǎn)地 進口 規(guī)格 100ul
級別 化工級 證書 ISO系列證書
該抗體是針對HMGB1的兔多克隆抗體。在免疫組織化學(xué)染色和免疫印跡實驗中能識別HMGB1。
高遷移率族蛋白1(HMGB1)多克隆抗體 產(chǎn)品信息

高遷移率族蛋白1(HMGB1)多克隆抗體

Polyclonal Antibody to High Mobility Group Protein 1 (HMGB1)

HMG1; HMG3; SBP1; Sulfoglucuronyl Carbohydrate Binding Protein; Amphoterin; High Mobility Group Box 1 Protein

  • 編號PAA399Ra01

  • 物種Rattus norvegicus (Rat，大鼠) 相同的名稱，不同的物種。

  • 來源多抗制備

  • 宿主兔

  • 效價-

  • Ig類型IgG

  • 純化方式抗原特異性親和純化

  • 標(biāo)記物無標(biāo)記物

  • 免疫原RPA399Ra01-高遷移率族蛋白1(HMGB1)重組蛋白

  • 緩沖液成份0.01M 磷酸鹽緩沖液（pH7.4，containing 0.05% Proclin-300，50% glycerol）

  • 性狀液體

  • 濃度0.34mg/ml

  • 且適物種Homo sapiens (Human，人), Mus musculus (Mouse，小鼠)

  • 應(yīng)用WB,IHC
    如果抗體需用于流式細胞術(shù)，請參見流式抗體。

  • 下載英文說明書   中文說明書

  • 規(guī)格20µl100µl 200µl 1ml 10ml

  • 價格￥ 1436


特異性

該抗體是針對HMGB1的兔多克隆抗體。在免疫組織化學(xué)染色和免疫印跡實驗中能識別HMGB1。

用法

Western blotting: 0.5-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

儲存

經(jīng)常使用則4°C保存。-20°C保存不超過兩年。避免反復(fù)凍融。



穩(wěn)定性

熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有明顯的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲，損失率低于5%。

參考文獻

雜志參考文獻
Scandinavian Journal of Trauma, Resuscitation and Emergency MedicineHigh mobility group box protein-1 (HMGB-1) as a new diagnostic marker in patients with acute appendicitis [PubMed: PMC3094252]
RespirationProtective Effect of Nicotine on Lipopolysaccharide-Induced Acute Lung Injury in Mice [Karger: 000319151]
SurgeryClinical relevance of single nucleotide polymorphisms of the high mobility group box 1 protein gene in patients with major trauma in Southwest China [Pubmed: 22047946]
Viral ImmunologyIs HMGB1 a New Indirect Marker for Revealing Fibrosis in Chronic Hepatitis and a New Therapeutic Target in Treatment? [Wiley: source]
Chinese Medical JournalSeverity of sepsis is correlated with the elevation of serum high-mobility group box 1 in rats [CMJ: 2009218808935901080]
Microbiology and ImmunologyDiagnostic value of serum concentrations of high-mobility group-box protein 1 and soluble hemoglobin scavenger receptor in brucellosis [PubMed: 23278480]
ACTA biochimica polonicaHigh mobility group B1 levels in sepsis and disseminated intravascular coagulation [Actabp: Source]
Anesthesia and AnalgesiaThe Inhibitory Effect of Lidocaine on the Release of High Mobility Group Box 1 in Lipopolysaccharide-Stimulated Macrophages [PubMed: 21288974]
Rheumatology InternationalElevated serum levels of high mobility group box protein 1 (HMGB1) in patients with ankylosing spondylitis and its association with disease activity and quality of life [PubMed: 23143556]
Inflammation ResearchMammalian target of rapamycin complex 2 regulates inflammatory response to stress [PubMed: 22899279]
Acta Biochimica et Biophysica SinicaIGF-1 alleviates ox-LDL-induced inflammation via reducing HMGB1 release in HAECs [PubMed: 22782142]
LabVestThe suppression of TRIM21 and the accumulation of IFN-α play crucial roles in the pathogenesis of osteonecrosis of the femoral head. [PubMed: 22825687]
Biomark InsightsDecreased Epidermal Growth Factor (EGF) Associated with HMGB1 and Increased Hyperactivity in Children with Autism [PubMed: PMC3623607]
Evidence-based Complementary and Alternative MedicineATF3 Protects against LPS-Induced Inflammation in Mice via Inhibiting HMGB1 Expression [PubMed: PMC3770047]
Exp Ther MedCorrelation between serum high-mobility group box-1 levels and high-sensitivity C-reactive protein and troponin I in patients with coronary artery disease [Pubmed: 23935732]
International of Rheumatic disesasesSerum levels of high mobility group box 1 protein and its association with quality of life and psychological and functional status in patients with fibromyalgia [Pubmed: 23901875]
SurgeryA novel serum marker for biliary tract cancer: Diagnostic and prognostic values of quantitative evaluation of serum mucin 5AC (MUC5AC) [Pubmed: 24468034]
Acta Pharmacol Sin.Simvastatin suppresses vascular inflammation and atherosclerosis in ApoE-/- mice by downregulating the HMGB1-RAGE axis [Pubmed: 23564080]
BMC pulmonary medicineSoluble receptor for advanced glycation end-products and progression of airway disease [Pubmed: 24758342]
Biochemical Pharmacology

Ascorbic acid reduces HMGB1 secretion in lipopolysaccharide-activated RAW 264.7 cells and improves survival rate in septic mice by activation of Nrf2/HO-1 signals [Pubmed:25896849]




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