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聯(lián)系我時(shí),請(qǐng)告知來(lái)自 制藥網(wǎng)CAS號(hào) | 58970-76-6 | 產(chǎn)地 | 國(guó)產(chǎn) |
---|---|---|---|
級(jí)別 | 化工級(jí) |
Ubenimex (INN), also known more commonly as bestatin, is a competitive, reversible protease inhibitor. It is an inhibitor of arginyl aminopeptidase (aminopeptidase B), leukotriene A4 hydrolase (a zinc
烏苯美司
CAS:58970-76-6
英文名稱:Ubenimex
別名:貝他定;N-[(2S,3R)-3-氨基-2-羥基-4-苯丁酰]-L-亮氨酸;威迪凱;[S-(R*,S*)]-N-(3-氨基-2-羥基-1-氧代-4-苯丁基)-L-亮氨酸;苯丁抑制素
保存:2-8℃
分子式:C16H24N2O4
分子量:308.377
MDL:MFCD00083262
熔點(diǎn):233-236℃
用途:氨基肽酶的抑制劑。急、慢性細(xì)胞性白血病等病的輔助治療
Ubenimex (INN), also known more commonly as bestatin, is a competitive, reversible protease inhibitor. It is an inhibitor of arginyl aminopeptidase (aminopeptidase B), leukotriene A4 hydrolase (a zinc metalloprotease that displays both epoxide hydrolase and aminopeptidase activities), alanyl aminopeptidase (aminopeptidase M/N), leucyl/cystinyl aminopeptidase (oxytocinase/vasopressinase), and membrane dipeptidase (leukotriene D4 hydrolase). It is being studied for use in the treatment of acute myelocytic leukemia. It is derived from Streptomyces olivoreticuli. Ubenimex has been found to inhibit the enzymatic degradation of oxytocin, vasopressin, enkephalins, and various other peptides and compounds.
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