高速成像電生理分析系統(tǒng)

神經(jīng)生理、心血管病理生理研究中，經(jīng)常需要采集、記錄、分析生物電信號(hào)，觀察離體組織或是細(xì)胞中電活動(dòng)的變化。美國RedShirtImaging專注于高速成像技術(shù)，通過專業(yè)軟件對(duì)采集的生物電信號(hào)進(jìn)行分析處理，不僅可以獲得電信號(hào)變化的時(shí)間，還可以獲得電信號(hào)的空間分布以及傳播規(guī)律。使用圖像分析法記錄生物電信號(hào)的變化，結(jié)合高速成像技術(shù)與壓敏（或鈣敏）染料采集、分析、生物電信號(hào)，使用各種專用攝像頭結(jié)合軟件能將電信號(hào)記錄下來并經(jīng)過各種處理編輯成波形曲線，得到偽彩圖象和動(dòng)態(tài)圖像等，進(jìn)一步進(jìn)行各種復(fù)雜分析。是生理學(xué)、神經(jīng)生理學(xué)、心血管病理生理學(xué)研究的工具。

• 圖像法采集、記錄、分析生物電信號(hào)

• 不直接接觸組織或細(xì)胞，沒有機(jī)械刺激及破壞

• 精確度高、減小人為誤差

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Wright NJ, Sides LJ, Walling K. (2015) Initial studies on the direct and modulatory effects of nitric oxide on an identified central Helix aspersa neuron. Invert Neurosci. 15(1):175.

Sedmera D, Reckova M, Rosengarten C, Torres MI, Gourdie RG, Thompson RP. (2015) Optical Mapping of Electrical Activation in the Developing Heart. Microscopy and Microanalysis 11(3): 209-215.

Qian T, Chen R, Nakamura M, Furukawa T, Kumada T, Akita T, Kilb W, Luhmann HJ, Nakahara D, Fukuda A. (2014) Activity-dependent endogenous taurine release facilitates excitatory neurotransmission in the neocortical marginal zone of neonatal rats. Front Cell Neurosci. Feb 10;8:33.

Malyshev AY, Balaban PM (2014) Changes in Intracellular Calcium Ion Concentrations during Generation of High-Amplitude EPSP in Neurons in the Common Snail Neurosci Behav Physiol

Weigel S, Flisikowska T, Schnieke A, Luksch H. (2014) Hybrid voltage sensor imaging of eGFP-F expressing neurons in chicken midbrain slices. J Neurosci Methods. 233C:28-33.

Popovic MA, Gao X, Carnevale NT, Zecevic D. (2014) Cortical Dendritic Spine Heads Are Not Electrically Isolated by the Spine Neck from Membrane Potential Signals in Parent Dendrites. Cereb. Cortex 24 (2): 385-395.

Cantu D, Walker K, Andresen L, Taylor-Weiner A, Hampton D, Tesco G, Dulla CG. (2014) Traumatic Brain Injury Increases Cortical Glutamate Network Activity by Compromising GABAergic Control. Cereb. Cortex.