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Recombinant Human BMP-4 貨號(hào):120-05細(xì)胞因子

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Recombinant Human BMP-4 貨號(hào):120-05細(xì)胞因子
細(xì)胞因子(cytokine,CK)是一類能在細(xì)胞間傳遞信息、具有免疫調(diào)節(jié)和效應(yīng)功能的蛋白質(zhì)或小分子多肽。
作用特點(diǎn)：多效性、重疊性、協(xié)同性、拮抗性和雙重性。

詳細(xì)介紹

Recombinant Human BD-4 貨號(hào):300-65 細(xì)胞因子

 

細(xì)胞因子受體的結(jié)構(gòu)和分類:根據(jù)細(xì)胞因子受體cDNA序列以及受體胞膜外區(qū)氨基酸序列的同源性和結(jié)構(gòu)征，可將細(xì)胞因子受體主要分為四種類型：免疫球蛋白超家族（IGSF）、造血細(xì)胞因子受體超家族、神經(jīng)生長(zhǎng)因子受體超家族和趨化因子受體。

 

Catalog Number:
120-05
Synonyms:
BMP-2B, DVR4
Description:
Bone morphogenetic proteins （BMPs） constitute a subfamily within the TGF-β superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body and are involved in diverse physiological processes during both pre- and postnatal life. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Recombinant human BMP-4, expressed in HeLa cells, is a 31-36 kDa homodimeric glycoprotein.
AA Sequence:
HHSQRARKKN KNCRRHSLYV DFSDVGWNDW IVAPPGYQAF YCHGDCPFPL ADHLNSTNHA IVQTLVNSVN SSIPKACCVP SAISMLY LDEYDKVVLK NYQEMVVEGC GCR
Source:
HeLa cells
Purity:
Greater than 97% by SDS-PAGE gel and HPLC analyses.
Biological Activity:
Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells.
 
 
 
 
Cross Reactivity:
Human, Mouse, Rat
Research Interests:
Angiogenesis/ Cardiovascular Angiogenesis/ Cardiovascular Apoptosis Apoptosis
Bone, Skeletal, Cartilage Bone, Skeletal, Cartilage Proliferation Proliferation
Stem Cells & Differentiation Stem Cells & Differentiation TGF-β Superfamily TGF-β Superfamily
 
 
Country of Origin:
USA


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