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Recombinant Human Eotaxin-2(CCL24) 貨號:300-33 細(xì)胞因子

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Recombinant Human Eotaxin-2(CCL24) 貨號:300-33 細(xì)胞因子
細(xì)胞因子(cytokine,CK)是一類能在細(xì)胞間傳遞信息、具有免疫調(diào)節(jié)和效應(yīng)功能的蛋白質(zhì)或小分子多肽。
作用特點(diǎn):多效性、重疊性、協(xié)同性、拮抗性和雙重性。

詳細(xì)介紹

Recombinant Human Eotaxin-2(CCL24) 貨號:300-33 細(xì)胞因子

 

細(xì)胞因子受體的結(jié)構(gòu)和分類:根據(jù)細(xì)胞因子受體cDNA序列以及受體胞膜外區(qū)氨基酸序列的同源性和結(jié)構(gòu)征,可將細(xì)胞因子受體主要分為四種類型:免疫球蛋白超家族(IGSF)、造血細(xì)胞因子受體超家族、神經(jīng)生長因子受體超家族和趨化因子受體。

 

Catalog Number:
300-22
Synonyms:
Epithelial Neutrophil Activating Peptide-78, CXCL5
Description:
ENA-78 is a CXC chemokine that signals through the CXCR2 receptor. It is expressed in monocytes, plaets, endothelial cells, and mast cells. ENA-78 is a chemoattractant for neutrophils. The three naturally occurring variants of human ENA-78; ENA 5-78, ENA 9-78 and ENA 10-78, contain 74, 70, and 69 amino acid residues, respectively, and possess the same biological activity. ENA-78 contains the four conserved cysteine residues present in CXC chemokines, and also contains the 'ELR' motif common to CXC chemokine that bind to the CXCR1 and CXCR2 receptors. Recombinant human ENA-78 is an 8.0 kDa protein consisting of 74 amino acid residues.
AA Sequence:
AAVLRELRCV CLQTTQGVHP KMISNLQVFA IGPQCSKVEV VASLKNGKEI CLDPEAPFLK KVIQKILDGG NKEN
Source:
E.coli
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity:
Determined by its ability to chemoattract human peripheral blood neutrophils using a concentration of 5.0-10.0 ng/ml.
 
 
 
 
Cross Reactivity:
Hamster, Human, Bacteria
Research Interests:
Angiogenesis/ Cardiovascular Angiogenesis/ Cardiovascular Chemotaxis Chemotaxis
Inflammation Inflammation Wound Healing Wound Healing
 
 
Country of Origin:
USA


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