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Recombinant Human MIP-4(CCL18) 貨號(hào):300-34細(xì)胞因子

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Recombinant Human MIP-4(CCL18) 貨號(hào):300-34細(xì)胞因子
細(xì)胞因子(cytokine,CK)是一類(lèi)能在細(xì)胞間傳遞信息、具有免疫調(diào)節(jié)和效應(yīng)功能的蛋白質(zhì)或小分子多肽。
作用特點(diǎn):多效性、重疊性、協(xié)同性、拮抗性和雙重性。

詳細(xì)介紹

Recombinant Human MIP-4(CCL18) 貨號(hào):300-34細(xì)胞因子

 

胞因子受體存在著可溶性形式,掌握可溶性細(xì)胞因子受體產(chǎn)生的規(guī)律及其生理和病理意義,必將擴(kuò)展人們對(duì)細(xì)胞因子網(wǎng)絡(luò)作用的認(rèn)識(shí)。檢測(cè)細(xì)胞因子及其受體的水平已成為基礎(chǔ)和臨床免疫學(xué)研究中的一個(gè)重要的方面。Catalog Number:

 
Catalog Number:
300-34
Synonyms:
Macrophage Inflammatory Protein-4, CCL18, PARC, DC-CK1, AMAC-1
Description:
MIP-4 is a CC chemokine that is expressed in lymph nodes, lungs, placenta and bone marrow. MIP-4's primary receptor is unknown. MIP-4 chemoattracts lymphocytes, and has been shown to exert activity on both CD4+ and CD8+ T cells. Recombinant human MIP-4 is a 7.8 kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.
AA Sequence:
AQVGTNKELC CLVYTSWQIP QKFLVDYSET SPQCPKPGVI LLTKRGRQIC ADPNKKWVQK YISDLKLNA
Source:
E.coli
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity:
Assay #1: Determined by its ability to chemoattract human T lymphocytes using a concentration of 1.0-10.0 ng/ml.
Assay #2: Determined by its ability to chemoattract human iDCs using a concentration of 1.0-10.0 ng/ml.
 
 
 
 
Cross Reactivity:
Human + Mouse, Human, Leech, Bacteria
Research Interests:
Chemotaxis Chemotaxis Wound Healing Wound Healing
 
 


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