詳細(xì)介紹
英文名稱: Podophyllotoxin
中文名稱: 鬼臼毒素
MF: C22H22O8
MW: 414.41
CAS: 518-28-5
中文名稱:鬼臼毒素
中文同義詞:鬼臼毒素原粉;盾葉鬼臼;鬼臼毒素98%;鬼臼毒素原料藥生產(chǎn)廠商;鬼臼毒素原料粉;鬼臼毒素原料;鬼臼毒素雜質(zhì);鬼臼毒素(鬼臼脂毒
英文名稱:Podophyllotoxin
英文同義詞:Condyline;(5R,5aR,8aR,9R)-5,8,8a,9-Tetrahydro-9-hydroxy-5-(3,4,5-triMethoxyphenyl)-furo(3',4':6,7)naphtho[2,3-d]-1,3-dioxol-6(5aH);(5R,5aR,8aR,9R)-9-hydroxy-5-(3,4,5-triMethoxyphenyl)-5,5a,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(8H)-one;Podophyllotoxin(Podofilox);SinopodophylumhexandrumP.E.;(5R,5aR,8aR,9R)-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-5,8,8a,9-tetrahy;Podophyllotoxin(PPT);(5R,5AR,8aR,9R)-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-5,8,8a,9-tetrahydrofuro[3',4':6,7]naphtho
CAS號:518-28-5
分子式:C22H22O8
分子量:414.41
EINECS號:208-250-4
相關(guān)類別:中藥對照品;標(biāo)準(zhǔn)品;對照品,標(biāo)準(zhǔn)品;生化試劑;植物提取物;對照品;抗生素;小分子抑制劑;小分子抑制劑,天然產(chǎn)物;醫(yī)藥原料;有機(jī)原料;醫(yī)藥原料藥;原料藥;醫(yī)藥抗菌消炎;天然產(chǎn)物;植物成分單體;皮膚外用原料;農(nóng)業(yè)原料;Non-nucleosideReverseTranscriptase;Pharmaceuticals;chemicalreagent;pharmaceuticalintermediate;phytochemical;referencestandardsfromChinesemedicinalherbs(TCM).;standardizedherbalextract;CONDYLOX;NaturalPlantExtract;MicrotobuleInhibitorsCancerResearch;MicrotubuleInhibitors;AntitumorAgents;CellSignalingandNeuroscience;CytoskeletonandExtracellularMatrix;Anti-virals;Inhibitors;Intermediates&FineChemicals;PlantOils,Toxins,PhenolicAcids&Derivatives
化學(xué)性質(zhì) :白色針狀結(jié)晶,易溶于甲醇,來源于小檗科植物桃兒七屬植物桃兒七根莖部,小蘗科鬼臼屬植物---華鬼臼根和莖。
用途:一種微管組裝和DNA拓?fù)洚悩?gòu)酶II抑制劑。Podophyllotoxinisapotentinhibitorofmicrotubuleassemblythatbindsatthecolchicinesiteoftubulin.ChemicalbookItisanantineoplasticglucosideandantitumoragent.Also,podophyllotoxinisaTopoII(DNAtopoisomeraseII)andtubulininhibitor.
用途:主要用于尖銳濕疣,也可用于其他病毒疣
用途:抑制微導(dǎo)管(microtubule)組裝;抗腫瘤。臨床上用于急性單核細(xì)Chemicalbook胞型和急性粒單核細(xì)胞型白血病,急性粒細(xì)胞白血病,慢性嗜酸粒細(xì)胞型白血病,小細(xì)胞肺癌,非何杰金氏惡性淋巴瘤 等。