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詳細介紹
4-氯-DL-苯丙氨酸 Sigma
4-氯-DL-苯丙氨酸 Sigma
Application
4-Chloro-DL-phenylalanine has been used:
• as tryptophan hydroxylase 1 (TPH1) inhibitor to treat kras+ male zebrafish[2]
• to induce insomnia in rat models[3]
• used to treat embryos to examine its effect on serotonin[4]
• for the selection of Enterococcus faecalis transformants with pESentA32 plasmid[5]
• to feed flies to explore serotonin effect[6]
包裝
5, 25 g in poly bottle
Features and Benefits
該化合物也是Sigma藥理活性化合物庫（LOPAC®1280）的一部分，該化合物庫是一個具有生物學注釋的高品質(zhì)、可即時篩選化合物的集合。
性質(zhì)
| Related Categories | Chemical Synthesis, Enzyme Inhibitors, Greener Alternative Products, Neuroscience, Neurotransmission, Neurotransmitter Metabolism, Re−engineered Products, Tryptophan Hydroxylase, 細胞信號轉(zhuǎn)導和神經(jīng)科學, 細胞生物學 Less... |
| Quality Level | 100 |
| greener alternative product characteristics | Waste Prevention Designing Safer Chemicals Reduce Derivatives Learn more about the Principles of Green Chemistry. |
| mp | >240 °C (dec.) (lit.) |
| greener alternative category | Re-engineered |
| storage temp. | room temp |
| SMILES string | NC(Cc1ccc(Cl)cc1)C(O)=O |
| InChI | 1S/C9H10ClNO2/c10-7-3-1-6(2-4-7)5-8(11)9(12)13/h1-4,8H,5,11H2,(H,12,13) |
| InChI key | NIGWMJHCCYYCSF-UHFFFAOYSA-N |
| Gene Information | human ... TPH1(7166), TPH2(121278) |
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