雷莫蘆單抗Ramucirumab 是人 VEGFR-2 拮抗劑,可用于治療實體瘤。Ramucirumab 是一種人源化單克隆抗體,可與 VEGFR-2 結(jié)合,阻止 VEGFR 配體 VEGF-A,VEGF-C 和 VEGF-D 結(jié)合。
Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors. Ramucirumab is a recombinant human immunoglobulin G1 monoclonal antibody that binds to the extracellular binding domain of VEGFR-2 and prevents the binding of VEGFR ligands: VEGF-A, VEGF-C, and VEGF-D.
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