中文名稱:	他克莫司
中文同義詞:	大環(huán)哌喃;他克莫斯;泰克利馬;他克莫司FK-506;他克莫司(免疫抑制藥,皮炎);他克莫司;富吉霉素;藤毒素
英文名稱:	Tacrolimus
英文同義詞:	(2-propenyl)-,(3s-(3r(e(1s,3s,4s)),4s,5r,8s,9e,12r,14r,15s,16r,18s;,19s,26ar))-;16-dimethoxy-4,10,12,18-tetramethyl-8-3-(2-(4-hydroxy-3-methoxycyclohexyl)-1;19-epoxy-3h-pyrido(2,1-c)(1,4)oxaazacyclotricosine-1,7,20,21(4h,23h)-tetrone,5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-(2-(4-hydroxy-3-methoxycyclohexyl)-14,16-dim;6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-5;fr900506;prograf;tsukubaenolide
CAS號(hào):	104987-11-3
分子式:	C44H69NO12
分子量:	804.02
EINECS號(hào):
相關(guān)類別:	Dermatosis皮膚美容類;Active Pharmaceutical Ingredients;Immunosuppressant.;原料藥;Intermediates & Fine Chemicals;Pharmaceuticals;大環(huán)內(nèi)酰胺類抗生素;抗生素;藥物;科研試劑;免疫抑制劑;API;Chiral Reagents;中間體;信號(hào)轉(zhuǎn)導(dǎo)通路激酶抑制劑;中藥對(duì)照品;分析標(biāo)準(zhǔn)品;植物提取物;Fujimycin, Prograf;antibiotic;微生物代謝物;標(biāo)準(zhǔn)品;藥物標(biāo)準(zhǔn)品;中藥標(biāo)準(zhǔn)品;醫(yī)藥中間體;小分子抑制劑;Inhibitors;小分子抑制劑，天然產(chǎn)物;醫(yī)藥原料藥
Mol文件:	104987-11-3.mol

他克莫司性質(zhì)

熔點(diǎn)	113-115°C
儲(chǔ)存條件	−20°C
溶解度	DMSO: >3 mg/mL
form	solid
color	white
水溶解性	Freely soluble in DMSO or ethanol. Poorly soluble in water.Soluble in dimethyl sulfoxide, ethanol, water, acetone, chloroform, ethyl acetate, ether, methanol and dimethyl formamide.
CAS 數(shù)據(jù)庫(kù)	104987-11-3(CAS DataBase Reference)


用途	大環(huán)內(nèi)酯類抗生素。免疫抑制劑。作用機(jī)制和環(huán)孢菌素相同，主要是抑制白細(xì)胞介素-2的合成。