Recombinant Human OTOR 貨號(hào):130-03 細(xì)胞因子
胞因子受體存在著可溶性形式，掌握可溶性細(xì)胞因子受體產(chǎn)生的規(guī)律及其生理和病理意義，必將擴(kuò)展人們對(duì)細(xì)胞因子網(wǎng)絡(luò)作用的認(rèn)識(shí)。檢測(cè)細(xì)胞因子及其受體的水平已成為基礎(chǔ)和臨床免疫學(xué)研究中的一個(gè)重要的方面。Catalog Number:
Catalog Number:
130-03
Synonyms:
Otoraplin, MIAL
Description:
OTOR, also called Otoraplin and MIAL, is a secreted cytokine and a member of the MIA/OTOR family. Members of this family which also includes MIA, MIA2, and TANGO share a Src homology-3 （SH3）-like domain. OTOR is predominantly expressed in the cochlea of the inner-ear and to a lesser extent in fetal brain and in some cartilage tissues. OTOR appears to be involved in early chondrogenesis of the otic capsule, which is required for normal inner ear development and auditory function. Recombinant human OTOR is a 12.7 kDa globular protein containing 112 amino acid residues.
AA Sequence:
MVHGIFMDRL ASKKLCADDE CVYTISLASA QEDYNAPDCR FINVKKGI YVYSKLVKEN GAGEFWAGSV YGDGQDEMGV VGYFPRNLVK EQRVYQEATK EVPTTDIDFF CE
Source:
E.coli
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity:
Data Not Available.
Country of Origin:
USA
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